1. eukaryotes have a nucleus, while prokaryotes do not 2. eukaryotes have membrane-bound organelles, while prokaryotes do not. The organelles of eukaryotes allow them to exhibit much higher levels of intracellular division of labor than is possible in prokaryotic cells. 3. Eukaryotic cells are, on average, ten times the size of prokaryotic cells. 4. The DNA of eukaryotes is much more complex and therefore much more extnsive than the DNA of prokaryotes.