Direct spinothalamic pathway: the neospinothalamic tract. The peripheral processes of these dorsal root ganglion cells end as receptors sensing pain, temperature, and simple tactile sensations. The central processes of these dorsal root ganglion cells synapse with the neurons of the nucleus proprius. The axons of these second-order neurons cross via the anterior white commissure, enter the contralateral white matter, ascend in the lateral funiculus, and synapse on third-order neurons located ...