Thanos was subject to the Deviant gene at birth. As a result, Thanos became like that of a 'mutant' of Titan (the sixth moon of Saturn) where he developed a purple, hide-like skin which allowed him to absorb cosmic energy at an atomic level, then manipulate it into kinetic force by conscious choice. Along with strength and other physical abilities making him the most powerful Titan. The mutation also augmented the powers he possessed as a descendant of the Eternals.